Urology of St. Louis established the Advanced Prostate Cancer Center of Excellence to provide a special multidisciplinary approach to treatment using guidance from a dedicated urologist with subspecialty interest in prostate cancer.

The advanced prostate cancer center was created solely for men with advanced prostate cancer and their families. A team of dedicated urologic subspecialists, nurses, and radiation oncologists bring a special focus to helping you navigate all options for your best individualized treatment plan. Working together, the USL team will develop a treatment plan using the best available cutting-edge therapies specifically tailored for your unique situation.

advanced prostate cancer center


Advanced prostate cancer care often requires an individualized treatment plan using a combination of multiple therapies. As treatment options are always being developed, we continually monitor you and your prostate cancer to determine if you are a candidate for newly-offered beneficial therapies. Additionally, we participate in clinical research trials.

Jamie Whaley, Nurse Navigator

Jamie Whaley joined Urology of St. Louis in 2012 as an LPN. In 2019, she graduated from Lutheran School of Nursing with her RN and began as the Nurse Navigator for the Advanced Prostate Cancer Center. As the Nurse Navigator for over 20 urologists, Jamie is in direct line to help patients through the complicated disease state associated with prostate cancer. Jamie is passionate about assisting patients through their course of care from prostate cancer diagnosis through treatment and survivorship.

In her spare time, Jamie enjoys spending time with her husband and three daughters. She also enjoys traveling and crafting.


Treating Your Advanced Prostate Cancer

  • Androgen deprivation therapy (ADT)
  • Bone Therapies
  • Chemotherapy
  • Oral Medication
  • External beam radiation therapy
  • Provenge® (sipuleucel-T)
  • Xofigo®

Prostate cancer uses male testosterone to grow. ADT, or hormone therapy, works by lowering the body’s testosterone level to slow prostate cancer growth. ADT is often used to treat prostate cancer that has spread to other sites in the body. Side effects are possible, including fatigue, weight gain, weakened bones, muscle reduction, sexual dysfunction, and possible susceptibility to hot flashes.

Advanced prostate cancer as well as the treatments for it can weaken the bones and increase the risk of fractures. Prolia® and Xgeva® (denosumab) are bone-strengthening drugs that slow down the bone-weakening process. Vitamin D, calcium supplements, and regular exercise are also important for bone health.

Chemotherapy is sometimes combined with hormone therapy to treat prostate cancer that has spread into bones or other organs. 

There are a number of medications for treating cancer that has spread beyond the prostate: Nubeqa® (darolutamide), Erleada® (apalutamide), Xtandi® (enzalutamide), Zytiga® (abiraterone acetate). Often, these drugs are used when the cancer is no longer responding to androgen deprivation therapy or can be used if prostate cancer has spread outside of the prostate.

Radiation therapy can help relieve pain from prostate cancer that has spread to bones. It is also used to treat prostate cancer that has limited spread to other parts of the body. Radiation therapy is delivered by a radiation oncologist. Urology of St. Louis partners with various radiation centers of excellence for prostate cancer in the St. Louis metro area.

Provenge® is a medication used to treat prostate cancer that has spread outside of the prostate to other parts of the body. It is a unique medication for prostate cancer in that is a type of immunotherapy that activates the body’s immune system to find prostate cancer cells to attack them.

Xofigo® is a type of radiation therapy used to treat prostate cancer that has spread to bone and causes pain. It is delivered through an IV by a radiation oncologist. 

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